Anaplastic lymphoma kinase 5A4 immunohistochemistry as a diagnostic assay in lung cancer: A Canadian reference testing center's results in population-based reflex testing.
Pierre O FisetCatherine LabbéKelvin YoungKenneth J CraddockAdam C SmithJeffrey TanguayMelania PintilieRi WangEmina TorlakovicCarol CheungGilda da Cunha SantosHyang-Mi KoScott L BoernerDavid M HwangNatasha B LeighlMing Sound TsaoPublished in: Cancer (2019)
ALK 5A4 IHC can serve as a robust diagnostic test for ALK-rearranged lung cancer and is associated with treatment response and survival. Optimized tissue allocation resulted in high success rates of combined reflex EGFR and ALK testing.