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Whole-Genome Transcriptomics of PBMC to Identify Biomarkers of Early Metabolic Risk in Apparently Healthy People with Overweight-Obesity and in Normal-Weight Subjects.

Andrea CostaInge van der SteltBàrbara ReynésJadwiga KoniecznaMiquel FiolJaap KeijerAndreu PalouDora RomagueraEvert M van SchothorstPaula Oliver
Published in: Molecular nutrition & food research (2023)
PBMC gene expression analysis of CXCL8 or a pool of DEGs may be used to identify early metabolic risk in an apparently healthy population regardless of their BMI, i.e., subjects with OW-OB or MONW phenotype and to apply adequate and personalized nutritional preventive strategies.
Keyphrases
  • weight gain
  • gene expression
  • weight loss
  • body mass index
  • physical activity
  • metabolic syndrome
  • dna methylation
  • type diabetes
  • adipose tissue
  • high fat diet induced