FGF23 Concentration and APOL1 Genotype Are Novel Predictors of Mortality in African Americans With Type 2 Diabetes.

Gary C ChanJasmin DiversGregory B RussellCarl D LangefeldLynne E WagenknechtFang-Chi HsuJianzhao XuS Carrie SmithNicholette D D AllredPamela J HicksDonald W BowdenThomas C RegisterLijun MaJ Jeffrey CarrBarry I Freedman

Published in: Diabetes care (2017)

Accounting for conventional risk factors, higher FGF23 concentrations and APOL1 non-renal-risk genotypes associated with higher mortality in African Americans with diabetes. These data add to growing evidence supporting FGF23 association with mortality; mechanisms whereby these novel predictors impact survival remain to be determined.

Keyphrases

risk factors
cardiovascular events
type diabetes
metabolic syndrome
electronic health record
skeletal muscle
glycemic control