Optimization of risk stratification for anticoagulation-associated intracerebral hemorrhage: net risk estimation.
Vasileios-Arsenios LioutasNitin GoyalAristeidis H KatsanosChristos KrogiasRamin ZandVijay K SharmaPanayiotis VarelasKonark MalhotraMaurizio PaciaroniTheodore KarapanayiotidesAboubakar SharafJason ChangOdysseas KargiotisAbhi PandhiLina PalaiodimouChristoph SchroederArgyrios TsantesEfstathios BoviatsisChandan MehtaAspasia SerdariKonstantinos VadikoliasPanayiotis D MitsiasMagdy H SelimAndrei V AlexandrovGeorgios TsivgoulisPublished in: Journal of neurology (2019)
In this anticoagulation-associated ICH cohort, baseline hemorrhagic risk exceeded ischemic risk in approximately 50%, highlighting the importance of careful consideration of risk/benefit ratio prior to anticoagulation decisions. The remaining 50% suffered an ICH despite excess baseline ischemic risk, stressing the need for biomarkers to allow more precise estimation of hemorrhagic complication risk.