Associations of KCNQ1 Polymorphisms with the Risk of Type 2 Diabetes Mellitus: An Updated Meta-Analysis with Trial Sequential Analysis.

Xiao-Xuan Yu Min-Qi LiaoYu-Fei ZengXu Ping GaoYan-Hua LiuWei SunSui ZhuFang Fang Zeng Yan-Bin Ye

Published in: Journal of diabetes research (2020)

This meta-analysis suggested that KCNQ1 gene polymorphisms (rs2237892, rs2283228, rs2237895, rs151290, and rs2074196) might be the susceptible factors for T2DM, especially among Asian population.

Keyphrases

systematic review
clinical trial
study protocol
adipose tissue
case control
phase ii
skeletal muscle
weight loss
glycemic control