Long-term antigen-specific immune response by an oncolytic adenovirus encoding SP-SA-E7-4-1BBL in HPV-16 cancer model.

Alejandra G Martinez-PerezRodolfo Garza-MoralesMaria de J Loera-AriasSheila A Villa-CedilloAracely Garcia-GarciaHumberto Rodriguez-RochaOrlando E Flores-MaldonadoJesus ValdesJosé Juan Pérez-TrujilloOdila Saucedo-Cardenas

Published in: Molecular biology reports (2024)

The OAd SP-SA-E7-4-1BBL vaccine confers a prophylactic, safe, long-lasting, and antigen-dependent antitumor effect mediated by a Th1 antitumor immune response.

Keyphrases

immune response
papillary thyroid
dendritic cells
toll like receptor
squamous cell
high grade
lymph node metastasis
young adults