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Myeloid-Cell-Specific IL-6 Signaling Promotes MicroRNA-223-Enriched Exosome Production to Attenuate NAFLD-Associated Fibrosis.

Xin HouShi YinRuixue RenSiqi LiuLiang YongYuxiao LiuYu LiMing-Hua ZhengGeorge KunosBin GaoHua Wang
Published in: Hepatology (Baltimore, Md.) (2021)
Myeloid-specific IL-6 signaling inhibits LF through exosomal transfer of antifibrotic miR-223 into hepatocytes, providing therapeutic targets for NAFLD therapy.
Keyphrases
  • bone marrow
  • dendritic cells
  • acute myeloid leukemia
  • cell proliferation
  • cell therapy
  • long noncoding rna
  • liver injury
  • mesenchymal stem cells
  • drug induced
  • pulmonary fibrosis
  • smoking cessation