Spatial-temporal dynamic evolution of lewy body dementia by metabolic PET imaging.
Jiaqi NiuYan ZhongLe XueHaotian WangDaoyan HuYi LiaoXiaohui ZhangXiaofeng DouCongcong YuBo WangYuan SunMei TianHong ZhangJing WangPublished in: European journal of nuclear medicine and molecular imaging (2024)
F-FDG PET and data-driven model illustrated spatial-temporal dynamic evolution of LBD and categorized novel subtypes with different evolutionary patterns, clinical and imaging features in vivo. The evolution-related subtypes are associated with LBD clinical phenotypes, which supports the perspective of existence of distinct entities in LBD spectrum.