Vandetanib alters the tumoricidal capacity of human breast cancer stem cells via inhibiting vasculogenic capacity.

Sanya HaiatyMohammad-Reza RashidiMaryam AkbarzadehAhad BazmanyMostafa MostafazadehSaba NikanfarRoya ShabkhizanRostam RezaeianReza RahbarghaziMohammad Nouri

Published in: BioImpacts : BI (2022)

Vandetanib suppressed vasculogenic mimicry (VM) networking through blunting stemness properties, coincided with suppression of VE-cadherin in CSCs.

Keyphrases

cancer stem cells
endothelial cells
signaling pathway
cell migration
epithelial mesenchymal transition