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Antioxidant defense and oxidative damage vary widely among high-altitude residents.

Allison J JanochaSuzy A A ComhairBuddha BasnyatManiraj NeupaneAmha GebremedhinAnam KhanKristin S RicciRenliang ZhangSerpil C ErzurumCynthia M Beall
Published in: American journal of human biology : the official journal of the Human Biology Council (2017)
High-altitude residence alone does not associate with high antioxidant defenses; residence length appears to be influential. The single-generation upward migrant sample had the lowest defense and nearly the highest DNA damage. The two high-altitude resident samples with millennia of residence had higher defenses than the two with multiple or single generations of residence.
Keyphrases
  • dna damage
  • oxidative stress
  • anti inflammatory
  • patient safety
  • dna repair
  • innate immune
  • quality improvement