Potential Structural Biomarkers in 3D Images Validated by the First Functional Biomarker for Early Age-Related Macular Degeneration - ALSTAR2 Baseline.

Sohaib Fasih-AhmadZiyuan WangZubin MishraCharles VatanathamMark E ClarkThomas A SwainChristine A CurcioCynthia OwsleySriniVas R SaddaZhihong Jewel Hu

Published in: medRxiv : the preprint server for health sciences (2023)

The association with IZ area and RMDA in large-scale data is biologically plausible because retinoid availability and transfer at the interface attributed to IZ is rate-limiting for RMDA. This study supports the hypothesis that the IZ integrity provides insight into the health of photoreceptors and RPE in early AMD and is a potential new imaging biomarker.

Keyphrases

age related macular degeneration
human health
healthcare
public health
mental health
deep learning
electronic health record
optical coherence tomography
health information
risk assessment
machine learning
social media
artificial intelligence
data analysis