Silencing oncogene cell division cycle associated 5 induces apoptosis and G1 phase arrest of non-small cell lung cancer cells via p53-p21 signaling pathway.
Wei ShenDimin TongJie ChenHongxiang LiZeyang HuShuguang XuSufang HeZhen GeJianan ZhangQiqi MaoHang ChenGuodong XuPublished in: Journal of clinical laboratory analysis (2022)
In conclusion, CDCA5 regulated the cell cycle of NSCLC cells by mediating the p53-p21 signaling pathway, participating in the development and progression of NSCLC patients.
Keyphrases
- cell cycle
- induced apoptosis
- signaling pathway
- cell cycle arrest
- pi k akt
- small cell lung cancer
- end stage renal disease
- cell proliferation
- endoplasmic reticulum stress
- epithelial mesenchymal transition
- newly diagnosed
- ejection fraction
- chronic kidney disease
- advanced non small cell lung cancer
- oxidative stress
- cell death
- transcription factor
- prognostic factors
- bone marrow
- patient reported outcomes
- epidermal growth factor receptor