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The functional divergence between SPA1 and SPA2 in Arabidopsis photomorphogenesis maps primarily to the respective N-terminal kinase-like domain.

Song ChenLennart WirthmuellerJohannes StauberNiels LoryXu HoltkotteLisa LesonChristian SchenkelMargaret AhmadUte Hoecker
Published in: BMC plant biology (2016)
Our results show that the distinct activities and protein stabilities of SPA1 and SPA2 in light-grown seedlings are primarily encoded by their N-terminal kinase-like domains. Similarly, the different affinities of SPA1 and SPA2 for cry2 are explained by their respective N-terminal domain. Hence, after a duplication event during evolution, the N-terminal domains of SPA1 and SPA2 underwent subfunctionalization, possibly to allow optimal adaptation of growth and development to a changing light environment.
Keyphrases
  • tyrosine kinase
  • amino acid
  • plant growth