A Neurochemical and Electrophysiological Study on the Combined Effects of Caffeine and Nicotine in the Cortex of Rats.
Iman M MouradNeveen A NoorHaitham S MohammedHeba S Aboul EzzYasser A KhadrawyPublished in: Basic and clinical neuroscience (2021)
These findings suggest that caffeine and nicotine adversely exacerbate their stimulant effects manifested by the EEG changes mediated by increasing cholinergic transmission and disturbing the balance between the excitatory and inhibitory amino acids leading to oxidative stress.