Food supplementation with rice bran enzymatic extract prevents vascular apoptosis and atherogenesis in ApoE-/- mice.
Cristina Perez-TerneroM D HerreraU LaufsM Alvarez de SotomayorC WernerPublished in: European journal of nutrition (2015)
Long-term food supplementation with RBEE lowers cholesterol and prevents atherosclerotic plaque development in ApoE-/- mice. Differential regulation of vascular and MNC apoptosis and senescence were identified as potential mechanisms.
Keyphrases
- oxidative stress
- endoplasmic reticulum stress
- high fat diet induced
- cell cycle arrest
- human health
- cognitive decline
- high fat diet
- dna damage
- coronary artery disease
- mouse model
- hydrogen peroxide
- risk assessment
- skeletal muscle
- nitric oxide
- signaling pathway
- climate change
- mild cognitive impairment
- cell proliferation
- pi k akt
- anti inflammatory