Tree House Explorer: A Novel Genome Browser for Phylogenomics.

Andrew J HarrisNicole M FoleyTiffani L WilliamsWilliam J Murphy

Published in: Molecular biology and evolution (2022)

Tree House Explorer (THEx) is a genome browser that integrates phylogenomic data and genomic annotations into a single interactive platform for combined analysis. THEx allows users to visualize genome-wide variation in evolutionary histories and genetic divergence on a chromosome-by-chromosome basis, with continuous sliding window comparisons to gene annotations (GFF/GTF), recombination rates, and other user-specified, highly customizable feature annotations. THEx provides a new platform for interactive phylogenomic data visualization to analyze and interpret the diverse evolutionary histories woven throughout genomes. Hosted on Conda, THEx integrates seamlessly into new or pre-existing workflows.

Keyphrases

genome wide
copy number
dna methylation
electronic health record
high throughput
big data
machine learning
gene expression
deep learning
dna damage
dna repair
oxidative stress
artificial intelligence
electron microscopy