Sulforaphane Ameliorates Limb Ischemia/Reperfusion-Induced Muscular Injury in Mice by Inhibiting Pyroptosis and Autophagy via the Nrf2-ARE Pathway.
Huanhuan SunJueqiong WangWei BiFeng ZhangKui ChiLong ShiTao YuanKai MaXiang GaoPublished in: Evidence-based complementary and alternative medicine : eCAM (2022)
SFN activates the Nrf2-ARE pathway, and thereby inhibits pyroptosis and autophagy and provides a novel therapeutic strategy for the limb I/R-induced muscle tissue damage.