Effects of clinically relevant radionuclides on the activation of a type I interferon response by radiopharmaceuticals in syngeneic murine tumor models.
Caroline P KerrJulia Sheehan-KlenkJoseph J GrudzinskiDavid P AdamThanh Phuong T NguyenCarolina A FerreiraAmber M BatesWon Jong JinOhyun KwonAeli P OlsonWilson LinMeredith HyunJustin C JagodinskyMaria PowersRaghava N SriramaneniPaul A ClarkAmanda G SheaHansel Comas RojasCynthia ChoiChristopher F MasseyLuke M ZanglAnatoly N PinchukEduardo Aluicio-SarduyKyungMann KimJonathan W EngleReinier HernandezBryan P BednarzJamey P WeichertZachary S MorrisPublished in: bioRxiv : the preprint server for biology (2024)
This study describes the time course and nature of tumor immunomodulation by radiopharmaceuticals with differing physical properties.
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