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Activation of upper respiratory tract mucosal innate immune responses in cats by liposomal toll-like receptor ligand complexes delivered topically.

William WheatLyndah ChowJonathan CoyElena T ContrerasMichael R LappinSteven Dow
Published in: Journal of veterinary internal medicine (2019)
Liposome-TLR complexes were found to effectively activate innate immune responses in cats after mucosal administration. These findings suggest that LTC have potential for use as a new mucosally administered immunotherapy for nonspecific protection from viral and bacterial respiratory tract infections.
Keyphrases
  • respiratory tract
  • toll like receptor
  • immune response
  • innate immune
  • nuclear factor
  • ulcerative colitis
  • inflammatory response
  • dendritic cells
  • sars cov
  • risk assessment