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Can human papillomavirus (HPV) genotyping classify non-16/18 high-risk HPV infection by risk stratification?

Yeoun-Eun SungEun Young KiYoun Soo LeeSoo Young HurAh Won LeeJong Sup Park
Published in: Journal of gynecologic oncology (2016)
The 12 non-16/18 HR-HPV genotypes can be further categorized (HPV-31/33/35/45/52/58 vs. HPV-39/51/56/59/66/68) by risk stratification. The HPV-31/33/35/45/52/58 genotypes might need more aggressive action. Large scale clinical trials or cohort studies are necessary to confirm our suggestion.
Keyphrases
  • high grade
  • clinical trial
  • cervical cancer screening
  • gene expression
  • dna methylation
  • genome wide