Performance of p16/Ki67 Immunostaining for Triage of Elderly Women with Atypical Squamous Cells of Undetermined Significance.
Maria Teresa BrunoArianna GuaitaSara BoemiGabriele MazzaMaria Chiara SudanoMarco PalumboPublished in: Journal of clinical medicine (2023)
Given the low sensitivity of cytology and the low percentage of HPV16-positive cancers among elderly women, triage via cytology and genotyping is not the best strategy; double staining cytology shows high profiles of sensibility and specificity for CIN2+ in ASCUS postmenopausal women.
Keyphrases
- high grade
- postmenopausal women
- fine needle aspiration
- low grade
- emergency department
- bone mineral density
- middle aged
- ultrasound guided
- induced apoptosis
- cell cycle arrest
- community dwelling
- polycystic ovary syndrome
- high throughput
- type diabetes
- genome wide
- squamous cell carcinoma
- endoplasmic reticulum stress
- pregnancy outcomes
- oxidative stress
- genetic diversity
- young adults
- neoadjuvant chemotherapy
- signaling pathway
- pregnant women
- skeletal muscle
- lymph node
- metabolic syndrome
- adipose tissue
- flow cytometry
- insulin resistance