Identification of clinical prognosis features and significant DNA methylation regulation in pineoblastoma.

Kongfeng ShaoHaojie ZhuXijin LinQiandong LiangZhanquan LeiBo GaoHaiyan ChenHui Zhang

Published in: International journal of clinical oncology (2024)

The prognosis of PB is closely associated with sex, age and receipt of radiotherapy, potentially linked to aberrations in the RAS and MAPK signaling pathways. The individual case suggests that dasatinib and trametinib are potential targeted therapies for improving PB prognosis.

Keyphrases

signaling pathway
dna methylation
heavy metals
pi k akt
early stage
radiation therapy
gene expression
oxidative stress
copy number
aqueous solution
cell proliferation
climate change
rectal cancer