Age-associated mRNA expression changes in bovine endometrial cells in vitro.

Nao TanikawaAyaka OhtsuRyouka Kawahara-MikiKoji KimuraShuichi MatsuyamaHisataka IwataTakehito KuwayamaKoumei Shirasuna

Published in: Reproductive biology and endocrinology : RB&E (2017)

Endometrial cells obtained from aged cows exhibited higher levels of inflammatory- and IFN-signaling, and dysfunction of cell division compared with young cows. In addition, a high basal level of IFN-related genes in endometrial cells of aged cows is suggested a concept of "inflammaging".

Keyphrases

induced apoptosis
cell cycle arrest
oxidative stress
dendritic cells
endometrial cancer
signaling pathway
endoplasmic reticulum stress
stem cells
cell proliferation