Age-associated mRNA expression changes in bovine endometrial cells in vitro.
Nao TanikawaAyaka OhtsuRyouka Kawahara-MikiKoji KimuraShuichi MatsuyamaHisataka IwataTakehito KuwayamaKoumei ShirasunaPublished in: Reproductive biology and endocrinology : RB&E (2017)
Endometrial cells obtained from aged cows exhibited higher levels of inflammatory- and IFN-signaling, and dysfunction of cell division compared with young cows. In addition, a high basal level of IFN-related genes in endometrial cells of aged cows is suggested a concept of "inflammaging".