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Age-associated mRNA expression changes in bovine endometrial cells in vitro.

Nao TanikawaAyaka OhtsuRyouka Kawahara-MikiKoji KimuraShuichi MatsuyamaHisataka IwataTakehito KuwayamaKoumei Shirasuna
Published in: Reproductive biology and endocrinology : RB&E (2017)
Endometrial cells obtained from aged cows exhibited higher levels of inflammatory- and IFN-signaling, and dysfunction of cell division compared with young cows. In addition, a high basal level of IFN-related genes in endometrial cells of aged cows is suggested a concept of "inflammaging".
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • oxidative stress
  • dendritic cells
  • endometrial cancer
  • signaling pathway
  • endoplasmic reticulum stress
  • stem cells
  • cell proliferation