Efficient production of myo-inositol in Escherichia coli through metabolic engineering.
Ran YouLei WangCongrong ShiHao ChenShasha ZhangMeirong HuYong TaoPublished in: Microbial cell factories (2020)
The biosynthesis of inositol from glucose in recombinant E. coli was optimized by metabolic engineering strategies. The metabolically engineered E. coli strains represent a promising method for future inositol production. This study provides an essential reference to obtain a suitable distribution of carbon flux between glycolysis and inositol synthesis.