BV associated bacteria specifically BVAB 1 and BVAB 3 as biomarkers for HPV risk and progression of cervical neoplasia.
Kavitha NaidooNathlee S AbbaiPartson TinarwoMotshedisi SebitloanePublished in: Infectious diseases in obstetrics and gynecology (2022)
There is a significant association of <i>A. vaginae</i>, BVAB 1, BVAB 3, <i>S. sanguinegens</i> and <i>Lactobacillus</i> spp to prevalent hrHPV. BVAB 1, BVAB 3 and <i>S. sanguinegens</i> had an increased odds for increasing CIN severity. <i>A vaginae</i>, BVAB 1, gravida and all the HPV genotypes/groups were significantly associated with HPV persistence. Only BVAB 3 and HPV 16 were significantly associated with hrHPV reinfection at 1 year review. BVAB 1 and BVAB 3 are possible biomarkers for HPV infection and CIN progression.