Crosslink between p53 and metastasis: focus on epithelial-mesenchymal transition, cancer stem cell, angiogenesis, autophagy, and anoikis.
Ghader BabaeiAzadeh AliarabMehdi Asghari VostakolaeiMasumeh HotelchiRoghaiyeh NeisariShiva Gholizadeh-Ghaleh AzizMasumeh Rajabi BazlPublished in: Molecular biology reports (2021)
Taken together, targeting mutant-p53 by altering the processes involved in metastasis could be a potential therapeutic strategy in the treatment of metastatic cancer.
Keyphrases
- epithelial mesenchymal transition
- cancer stem cells
- signaling pathway
- papillary thyroid
- squamous cell carcinoma
- small cell lung cancer
- cell death
- endothelial cells
- oxidative stress
- transforming growth factor
- endoplasmic reticulum stress
- vascular endothelial growth factor
- cancer therapy
- combination therapy
- lymph node metastasis
- young adults
- wild type
- drug delivery
- replacement therapy