Impression cytology of ocular surface in xeroderma pigmentosum.
Allexya Affonso Antunes MarcosDenise de FreitasJeison de Nadai BarrosArthur Gustavo FernandesMárcia LowenMoacyr RigueiroMelina Correia MoralesRubens Mattos Belfort NetoArun D SinghPublished in: Arquivos brasileiros de oftalmologia (2024)
Impression cytology has a moderate positive predictive value for the diagnosis of ocular surface squamous neoplasia in patients with xeroderma pigmentosum. However, the lack of detection of atypical cells on impression cytology has a high negative predictive value for ocular surface squamous neoplasia. Integration of impression cytology in the long-term management of high-risk patients, such as patients with xeroderma pigmentosum, can avoid unnecessary diagnostic biopsies.
Keyphrases
- high grade
- low grade
- fine needle aspiration
- end stage renal disease
- ultrasound guided
- ejection fraction
- induced apoptosis
- chronic kidney disease
- newly diagnosed
- prognostic factors
- cell cycle arrest
- high intensity
- oxidative stress
- signaling pathway
- patient reported outcomes
- endoplasmic reticulum stress
- patient reported
- loop mediated isothermal amplification
- label free