Lipase and factor V (but not viral load) are prognostic factors for the evolution of severe yellow fever cases.

Luciana Vilas Boas CasadioAna Paula Moreira SallesFernanda de Mello MaltaGabriel Fialkovitz LeiteYeh-Li HoMichele Soares Gomes-GouvêaLuiz Marcelo Sá MalbouissonAnna S LevinRaymundo Soares de Azevedo NetoFlair José CarrilhoAna Catharina Seixas Santos NastriJoão Renato Rebello Pinho

Published in: Memorias do Instituto Oswaldo Cruz (2019)

YF acute severe cases show a generalised involvement of different organs (liver, spleen, heart, kidneys, intestines and pancreas), and different parameters were related to outcome. Factor V and lipase are independent variables associated with death, reinforcing the importance of hemorrhagic events due to fulminant liver failure and pointing to pancreatitis as a relevant event in the outcome of the disease.

Keyphrases

liver failure
prognostic factors
hepatitis b virus
early onset
heart failure
drug induced
atrial fibrillation
intensive care unit
extracorporeal membrane oxygenation
aortic dissection