De Ritis-adjusted AST provides comparable efficacy to lactate dehydrogenase as a biomarker for detection of LVAD hemolysis or thrombosis.

Sarah D Schettle Andrew N Rosenbaum Daniel GoodmanJohn Stulak

Published in: Artificial organs (2022)

Both AST and LDH as well DRA are significantly associated with pump thrombosis (p < 0.0001 for each). DRA is a potential screening biomarker for hemolysis and device thrombosis in stable left ventricular assist device patients.

Keyphrases

left ventricular assist device
pulmonary embolism
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
risk assessment
patient reported outcomes
loop mediated isothermal amplification
human health