Hemorrhagic cystitis in allogeneic stem cell transplantation: a role for age and prostatic hyperplasia.

Eugenio GalliFederica SoràLuca Di GianfrancescoSabrina GiammarcoElisabetta MetafuniMaria Assunta LimongielloIdanna InnocentiFrancesco AutoreLuca LaurentiPatrizia ChiusoloAndrea BacigalupoSimona Sica

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2022)

Age is the most important risk factor for HC. Additional potential risk factors include cyclophosphamide-based GVHD prophylaxis and HLA mismatch. Among male recipients, prostatic hyperplasia is an additional independent risk factor. As HC is common and associated with prolonged hospitalization, more intensive prophylactic strategies should be considered in high-risk patients.

Keyphrases

stem cell transplantation
risk factors
high dose
end stage renal disease
chronic kidney disease
low dose
ejection fraction
newly diagnosed
benign prostatic hyperplasia
peritoneal dialysis
radical prostatectomy
prognostic factors
acute lymphoblastic leukemia
climate change