Brain-derived neurotrophic factor is elevated in the blood serum of Crohn's disease patients, but is not influenced by anti-TNF-α treatment-A pilot study.

Marcin Sochal Ewa Małecka-Panas Agata Gabryelska Jakub Fichna Renata Talar-Wojnarowska Bartosz M Szmyd Piotr Białasiewicz

Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2020)

Increased BDNF level in CD patients suggests that it may be involved in the pathogenesis and clinical course of the disease. Further research into BDNF might contribute to a better understanding of the effects of sleep and pain on the course of CD.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
rheumatoid arthritis
chronic pain
spinal cord injury
depressive symptoms
patient reported outcomes
spinal cord
stress induced
neuropathic pain
sleep quality
smoking cessation