Global Outcome Assessment Life-long after stroke in young adults initiative-the GOAL initiative: study protocol and rationale of a multicentre retrospective individual patient data meta-analysis.
Merel Sanne EkkerMina A JacobMyrna M E van DongenKaroliina AarnioArunkar K AnnamalaiAntonio ArauzMarcel ArnoldMiguel A BarbozaManuel BologneseRaf BrounsBatnairamdal ChuluunEnkhzaya ChuluunbaatarByambasuren DagvajantsanStephanie DebetteAdi DonChris EnzingerEsme EkizogluSimon Fandler-HöflerFranz FazekasAnette FrommThomas GattringerGiosue GulliMichael HoffmannThiago F HoraChristina JernKatarina JoodMasahiro KamouchiYoung Seo KimTakanari KitazonoSteven J KittnerTimothy J KleinigCatharina J M KlijnJanika KorvTsong-Hai LeeDidier LeysNoortje A M MaaijweeNicolas Martinez-MajanderJoão Pedro MartoMan M MehndirattaVictoria MifsudVinicius V MontanaroMayowa O OwolabiVinod B PatelMatthew C PhillipsBartlomiej Piechowski-JozwiakAleksandra PikulaJose Luis Ruiz-SandovalBettina SarnowskiFloris H B M SchreuderRick H SwartzK S TanDavid TanneT TatlisumakVincent ThijsAnil M TuladharMiguel Viana-BaptistaRiina ViboTeddy Y WuNilüfer YesilotUlrike Waje-AndreassenAlessandro PezziniJukka PutaalaFrank-Erik de LeeuwPublished in: BMJ open (2019)
Ethical approval for the GOAL study has already been obtained from the Medical Review Ethics Committee region Arnhem-Nijmegen. Additionally and when necessary, approval will also be obtained from national or local institutional review boards in the participating centres. When needed, a standardised data transfer agreement will be provided for participating centres. We plan dissemination of our results in peer-reviewed international scientific journals and through conference presentations. We expect that the results of this unique study will lead to better understanding of worldwide differences in risk factors, causes and outcome of young stroke patients.