Improvement by Medication Less than Expected in Parkinson's Disease: Blinded Evaluation of Levodopa Response.
Mette Niemann JohansenAnna HandbergMohamed El HaddouchiJosefine GrundtvigSteen Rusborg JensenLisette SalvesenAnnemette LøkkegaardPublished in: Parkinson's disease (2024)
We showed an acute effect of levodopa using LDCT that was around 30% improvement. While it lends support to the use of this limit in the MDS diagnostic criteria, an acute effect of less than 30% should be considered acceptable in some patients. Our study highlights a discrepancy in the objective measure of medicine effect on motor symptoms and the patient's subjective evaluation.
Keyphrases
- liver failure
- end stage renal disease
- parkinson disease
- respiratory failure
- ejection fraction
- deep brain stimulation
- chronic kidney disease
- newly diagnosed
- drug induced
- aortic dissection
- prognostic factors
- case report
- sleep quality
- peritoneal dialysis
- hepatitis b virus
- clinical trial
- extracorporeal membrane oxygenation
- depressive symptoms
- physical activity
- acute respiratory distress syndrome
- clinical evaluation