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Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks.

Sebastian ProftJanna LeizUdo HeinemannDominik SeelowKai M Schmidt-OttMaria Rutkiewicz
Published in: BMC genomics (2023)
Our results show that convolutional recurrent neural networks may uncover unanticipated binding sites and facilitate quantitative transcription factor binding predictions.
Keyphrases
  • neural network
  • transcription factor
  • dna binding
  • small molecule
  • high resolution
  • high throughput
  • mass spectrometry