ALPL Genotypes in Patients With Atypical Femur Fractures or Other Biochemical and Clinical Signs of Hypophosphatasia.

Francesca MariniLaura MasiFrancesca GiustiLuisella CianferottiFederica CioppiGemma MarcucciSimone CiuffiEmmanuel BiverGiuseppe ToroGiovanni IolasconTeresa IantomasiMaria Luisa Brandi

Published in: The Journal of clinical endocrinology and metabolism (2022)

The results suggest homozygosity of common ALPL variants as a possible genetic mark of risk for these fractures.

Keyphrases

copy number
genome wide
replacement therapy
bone mineral density
gene expression
body composition