Preclinical assessment of MAGMAS inhibitor as a potential therapy for pediatric medulloblastoma.
Zahra MotahariJavier J LepeMalia R BautistaClay HoerigAshley S Plant-FoxBhaskar DasChristie D FowlerSuresh N MaggeDaniela A BotaPublished in: bioRxiv : the preprint server for biology (2024)
data showed BT9 antitumor efficacy in DAOY and D425 cell lines suggesting that BT9 may represent a promising targeted therapeutic in pediatric medulloblastoma. These data, however, need to be further validated in animal models.