A Sputum 6 Gene Expression Signature Predicts Inflammatory Phenotypes and Future Exacerbations of COPD.
Katherine Joanne BainesNetsanet A NegewoPeter G GibsonJuan-Juan FuJodie Louise SimpsonPeter A B WarkMichael FrickerVanessa Marie McDonaldPublished in: International journal of chronic obstructive pulmonary disease (2020)
6GS can significantly and reproducibly discriminate COPD inflammatory phenotypes and predict exacerbation prone patients and may become a useful molecular diagnostic tool assisting COPD management.
Keyphrases
- chronic obstructive pulmonary disease
- lung function
- gene expression
- end stage renal disease
- cystic fibrosis
- ejection fraction
- chronic kidney disease
- oxidative stress
- newly diagnosed
- peritoneal dialysis
- dna methylation
- mycobacterium tuberculosis
- prognostic factors
- current status
- patient reported outcomes
- pulmonary tuberculosis