Intravesical hyaluronic acid treatment improves bacterial cystitis and reduces cystitis-induced hypercontractility in rats.
Nurdan YıldızHarika AlpayHalil TuğtepeZarife Nigar Özdemir KumralDilek AkakınArzu İlkiGöksel ŞenerBerrak Ç YeğenPublished in: International journal of urology : official journal of the Japanese Urological Association (2015)
Gentamycin treatment, despite its ameliorative effect on inflammation, had no impact on the contractile dysfunction of the injured bladder. Intravesical hyaluronic acid, in addition to its supportive role in the healing of the epithelium, seems to lower the increased threshold for contraction and to reduce oxidative stress. These findings support a potential role for hyaluronic acid in the treatment of bacterial cystitis.