Randomized Trial of Four Treatment Approaches for Actinic Keratosis.
Maud H E JansenJanneke P H M KesselsPatty J NelemansNina KouloubisAimee H M M AritsHan P A van PeltPatricia J F QuaedvliegBrigitte A B EssersPeter M SteijlenNicole W J Kelleners-SmeetsKlara MosterdPublished in: The New England journal of medicine (2019)
At 12 months after the end of treatment in patients with multiple actinic keratosis lesions on the head, 5% fluorouracil cream was the most effective of four field-directed treatments. (Funded by the Netherlands Organization for Health Research and Development; ClinicalTrials.gov number, NCT02281682.).
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