Genetic Predisposition to Neurological Complications in Patients with COVID-19.
Nikhil Shri SahajpalAlex R HastieMaximilian SchieckAshis K MondalMarc FeldeCaspar I van der MadeJanet S ChouAdrienne G RandolphThomas IlligMichael C ZodyCatherine A BrownsteinAlan H BeggsAlexander HoischenAlka ChaubeyRavindra Kolhenull nullPublished in: Biomolecules (2023)
Several studies have identified rare and common genetic variants associated with severe COVID-19, but no study has reported genetic determinants as predisposition factors for neurological complications. In this report, we identified rare/unique structural variants (SVs) implicated in neurological functions in two individuals with neurological manifestations of COVID-19. This report highlights the possible genetic link to the neurological symptoms with COVID-19 and calls for a collective effort to study these cohorts for a possible genetic linkage.