Detection of NRAS mutation in cell-free DNA biological fluids from patients with kaposiform lymphangiomatosis.
Michio OzekiYoko AokiAkifumi NozawaShiho YasueSaori EndoYumiko HoriKentaro MatsuokaTetsuya NiihoriRyo FunayamaMatsuyuki ShirotaKeiko NakayamaToshiyuki FukaoPublished in: Orphanet journal of rare diseases (2019)
These results provide the first evidence that NRAS oncogenic variant was identified in DNA samples from KLA patients from not only two affected lesions but also plasma and pleural effusion.