Optimal duration of first-line chemotherapy for advanced gastric cancer: data from the AGAMENON registry.
Antonio ViúdezA Carmona-BayonasJ GallegoA LacalleR HernándezJ M CanoI MacíasA CustodioE Martínez de CastroA SánchezL IglesiaP RegueraL VisaA AzkarateM Sánchez-CánovasM MangasM L LimónA Martínez-TorrónE AsensioA RamchandaniA Martín-CarniceroA HurtadoP CerdàM GarridoR Sánchez-BayonasR SerranoP Jiménez-Fonsecanull nullPublished in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2019)
The longer duration of the full initial regimen exerted a protective effect on the patients of this registry. Platinum discontinuation followed by fluoropyrimidine maintenance yields comparable efficacy to treatment up to PD, with a lower rate of serious adverse events.