Myoepithelial crowd control of cancer cells.

Published in: The Journal of cell biology (2018)

Smooth muscle-like cells can actively remodel epithelia, a mechanism common across developing tissues. In this issue, new work from Sirka et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201802144) demonstrates a novel mechanism for tumor suppression by smooth muscle-like myoepithelial cells of the mammary gland.

Keyphrases

smooth muscle
induced apoptosis
cell cycle arrest
single cell
cell therapy
endoplasmic reticulum stress
cell death
stem cells
mesenchymal stem cells
cell proliferation
pi k akt