Up-regulation of hsa-miR-221-3p induced by UVB affects proliferation and apoptosis of keratinocytes via Bcl-xL/Bax pathway.

Yunhua TuWen-Juan WuYanni GuoFengyan LuXing LiDan XuDandan ZouYing TuYanjie ChaiLi He

Published in: Photodermatology, photoimmunology & photomedicine (2021)

Hsa-miR-221-3p induced by UVB targeted FOS 3'UTR, which played an important role in regulating proliferation and apoptosis of keratinocytes via Bcl-xL/Bax pathway; this may provide a new insight for CAD proliferative lesions.

Keyphrases

endoplasmic reticulum stress
induced apoptosis
oxidative stress
cell cycle arrest
signaling pathway
cell death
coronary artery disease
wound healing
pi k akt