Serotonin neuromodulation directs optic nerve regeneration.
Kristian Saied-SantiagoMelissa BaxterJaffna MathiaparanamMichael GranatoPublished in: bioRxiv : the preprint server for biology (2024)
5-HT1 receptors selectively promote early optic nerve regrowth in zebrafish but are dispensable during development. Serotonin receptor-dependent modulation instructs regenerating optic nerve axons toward the brain in vivo.