Reduced bioavailability of oral amoxicillin tablets compared to suspensions in Roux-en-Y gastric bypass bariatric subjects.
Maiara Camotti MontanhaThiago Ferreira Dos Santos MagonConrado de Souza AlcantaraCaroline Ferraz SimõesSandra Regina Bin SilvaCristina Megumi KurodaSérgio Seiji YamadaLucas Eduardo Savóia de OliveiraDaoud NasserNelson Nardo JuniorJosmar MazucheliAndrea DinizPaulo Jorge Pereira Alves PaixãoElza KimuraPublished in: British journal of clinical pharmacology (2019)
The tablets presented a lower bioavailability than the suspension formulation and the total absorbed amount of AMX in these subjects was lower in comparison to the standard AMX absorption rates in nonbariatric subjects, regardless of the formulation.