Cardiovascular Measures of All-Cause Mortality in Duchenne Muscular Dystrophy.

Jonathan H SoslowMeng XuJames C SlaughterKimberly CrumJacob A Kaslow Kristen George-Durrett Frank J Raucci James D Wilkinson Linda H Cripe Kan N Hor Christopher F Spurney Larry W Markham

Published in: Circulation. Heart failure (2023)

LV ejection fraction, indexed LV volumes, circumferential strain, late gadolinium enhancement full width half maximum, and NT-proBNP are associated with all-cause mortality in DMD and may be the best end points for use in cardiovascular therapeutic trials. We also report change over time of cardiac magnetic resonance and blood biomarkers.

Keyphrases

duchenne muscular dystrophy
ejection fraction
magnetic resonance
aortic stenosis
muscular dystrophy
contrast enhanced
left ventricular
heart failure
computed tomography
aortic valve
transcatheter aortic valve replacement