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Using Hydrogel to Diversify the Adaptability and Applicability of Functional Nanoparticles: From Nanotech-Flavored Jellies to Artificial Enzymes.

Chongling ChengChuan ZhangDayang Wang
Published in: Langmuir : the ACS journal of surfaces and colloids (2019)
The use of hydrogel to accommodate nanoparticles is generally aimed at a synergetic integration of the peculiar electronic, photonic, magnetic, mechanical, and chemical properties of the nanoparticles with the stimuli-response of the hydrogels into unprecedented, smart, collective functions. The intrinsic water-borne nature of hydrogels further endorses the significant implications of such nanocomposites in biology and medicine. This article will be an account with a special accent on how to introduce nanoparticles within hydrogels and utilize the hydrogels to assist the nanoparticles to adapt themselves into different environments, with a large span of polarity ranging from orthodox aqueous media to unorthodox organic ones. The related technological developments and the associated fundamental issues will be discussed under the umbrella of enabling nanoparticle/hydrogel composites to emulate the unique catalytic performances of enzymes.
Keyphrases
  • drug delivery
  • hyaluronic acid
  • tissue engineering
  • wound healing
  • drug release
  • extracellular matrix
  • systematic review
  • reduced graphene oxide
  • iron oxide