Elevated serum levels of sialyl Lewis X (sLeX) and inflammatory mediators in patients with breast cancer.
Evan N CohenTamer M FouadBang-Ning LeeBanu K ArunDiane LiuSanda TinAngelica M Gutierrez BarreraToshihide MiuraIwao KiyokawaJun YamashitaRicardo H AlvarezVicente ValeroWendy A WoodwardYu ShenNaoto T UenoMassimo CristofanilliJames M ReubenPublished in: Breast cancer research and treatment (2019)
Elevated serum sLeX was associated with invasive cancer but not DCIS. High serum sLeX levels were associated with inflammatory mediators and may play a role in facilitating local invasion of breast tumor. Furthermore, serum MCP-1, IP-10 and sLeX may have prognostic value in breast cancer.