A Scoping Review of Focused Ultrasound Enhanced Drug Delivery for Across the Blood-Brain Barrier for Brain Tumors.
Christopher M YoungAriel Viña-GonzálezRodrigo Salmeron de Toledo AguiarCheyenne KalmanJulie Georgia PilitsisLaura I Martin-LopezTanmay MahaniJosé A Pineda-PardoPublished in: Operative neurosurgery (Hagerstown, Md.) (2024)
Here, we review the role of FUS in BBBO. Identified gaps in the literature include impact of tumor microenvironment and extracellular space, improved understanding and control of MB and drug delivery, further work on ideal pharmacologics for delivery, and clinical use.